One-step synthesis of diazaspiro[4.5]decane scaffolds with exocyclic double bonds.
نویسندگان
چکیده
Unactivated yne-en-ynes reacted with a range of substituted aryl halides in the presence of Pd(OAc)2-PPh3 to afford diazaspiro[4.5]decane with exocyclic double bonds. Three carbon-carbon bonds are formed in this domino reaction, which involves highly regioselective C-C coupling and spiro scaffold steps.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 29 شماره
صفحات -
تاریخ انتشار 2014